DNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIH "Random DNA" is naturally active in the one-celled fungi yeast, while such DNA is turned off as its ...
Human DNA constantly refolds in 3D space, and these looping dynamics regulate gene expression and cell identity.
Less than 2% of the genome codes for proteins; the rest, once called 'junk DNA', contains regulatory elements. Researchers analyzed 10,000 to reveal how variants shape gene activity.
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