Researchers from the University College London have brought us one step closer to understanding how we feel pain. Their study, published in Brain, describes a rare genetic mutation found in a patient ...

The research and development arm of Janssen Pharmaceuticals, a Johnson & Johnson company, announced on Sunday (January 17) their voluntary suspension of dosing in two Phase 2 clinical trials of their ...

Chronic cannabis users have reduced levels of an enzyme called fatty acid amide hydrolase (FAAH). The enzyme has been considered for treatment for cannabis dependence because it breaks down substances ...

Figure 1: An overview of the endocannabinoid pathway and molecules tested in this study. “This study explores the functional relevance and therapeutic potential of FAAH inhibition combined with the ...

Doctors in Scotland were amazed when a 66-year-old woman underwent what is normally a very painful operation on her hand for severe arthritis and required little to no pain medication afterward.

JO Cameron is one of only two people in the world who cannot feel pain, fear or anxiety. The pensioner’s rare genetic mutation also means her stress levels are almost non-existent and her wounds even ...

Fatty acid amide hydrolase (FAAH) is the main degrading enzyme of the fatty acid ethanolamides anandamide (AEA) and oleoylethanolamide (OEA), which have opposite effects on food intake and energy ...

A woman in Scotland can feel virtually no pain due to a mutation in a previously-unidentified gene, according to a research article. She also experiences very little anxiety and fear, and may have ...

The biology underpinning a rare genetic mutation that allows its carrier to live virtually pain-free, heal more rapidly and experience reduced anxiety and fear, has been uncovered by new research from ...

Scientists have learned more about a genetic disorder caused by a mutation in a gene called FAAH-OUT, in which carriers feel minimal or no pain, anxiety, or fear. The mutation reduces the expression ...

A Scottish woman in her 70s has lived a life without pain and fear. New research pinpoints unique mutations in her DNA. Reading time 3 minutes Scientists are starting to crack the mystery behind one ...