Scientists have known for decades that opioids relieve pain by binding to molecular switches in the brain called mu-opioid ...

A study from St. Jude Children's Research Hospital uncovered an alternative binding pocket within nuclear receptors, ...

Pfizer and Novo Nordisk are locked in a bidding war for biotech firm Metsera as the pharmaceutical giants seek to augment ...

Surprising findings published in PNAS have implications for understanding and treating neurological and neuropsychiatric disorders.

Opioid receptors are proteins in the nervous system that interact with opioids. Opioid receptors are part of the endogenous opioid system. This is the body’s internal system for regulating pain, ...

Adults with pulmonary arterial hypertension using vs. not using GLP-1 receptor agonists had significantly lower relative risks for mortality and respiratory failure, according to a presentation at the ...

A poorly characterized protein, historically thought to be a chaperon or enzyme, may actually be a key player in prostate ...

A once-daily oral quadruple receptor agonist induced up to 13.8% weight loss at 13 weeks among adults with overweight or ...

Drugs that act on NMDA (N-methyl-D-aspartate) receptors, which are essential for learning, memory and moment-by-moment consciousness, are key for treating neuropsychiatric disorders. These drugs were ...

GLP-1 receptor agonists like Ozempic and Wegovy are backed by solid scientific evidence and can support healthy weight management. But is it possible to get the same results from a supplement? GLP-1s ...