Week 13 was the most boring weekend of the season — by far. It had two ranked-on-ranked matchups (in Oregon-USC and Missouri-Oklahoma), and both games were decided by multiple scores. The higher-ranked team dispatched the lower-ranked opponent by doing what it does best. Ho-hum.

Since then, the Ducks have responded. It pulled out a gritty win at Iowa and cruised by Minnesota. In presenting its true case to the selection committee, No. 5 Oregon put a bow on it with a 42-27 defeat of No. 16 Southern California.

The ACC is full-blown disarray, the Big Ten and SEC are close to being decided but not quite, but somehow the Big 12 might be all but wrapped up after Week 13 i

Week 13 of the 2025 college football season kicks into full swing on Saturday afternoon with some exciting matchups across the country. Saturday’s schedule includes two ranked vs. ranked matchups, including four top 20 showdowns.

The Nebraska Huskers face the Penn State Nittany Lions on Saturday, Nov. 22, 2025 at Beaver Stadium in University Park, Pa.

Oregon Ducks injury updates before hosting the USC Trojans in Autzen Stadium. On ESPN's College GameDay, Pete Thamel confirmed that Oregon wide receivers Dakorien Moore and Gary Bryant Jr. will not play against USC.

Stanford can't keep up with Jaron-Keawe Sagapolutele and the California Golden Bears. Cal's spread anchors Andrew Caley's Triple Option and college football best bets for Week 13.

The Saturday college football schedule features crucial matchups for multiple teams, and the latest bet365 bonus code CBSBET365 gives new users $150 in bonus bets after placing a first wager of $5 or more.