The San Francisco 49ers are back in playoff contention with Brock Purdy returning as their starting quarterback.

Who will star for San Francisco on Monday Night Football? Here are some 49ers' bold predictions in their battle with the Panthers in Week 12.

In this week's "Monday Night Football" contest, the 49ers will wear their customized cleats on the field to amplify the causes close to their hearts off the field.

Rohit Ponnaiya breaks down his early Panthers vs. 49ers predictions ahead of Monday Night Football in Week 12. Free NFL picks for November 24.

Former Jets quarterback Ryan Fitzpatrick will make his debut as a color analyst when he calls Monday’s Carolina Panthers at San Francisco 49ers game for Westwood One Sports. The broadcast will mark Fitzpatrick’s first time working in the analyst booth for the radio network. He will team with play-by-play announcer Ryan Radtke for the game.

Mike Florio and Chris Simms unpack the Week 12 Sunday Night Football matchup between the Bucs and Rams, detailing why a vulnerable Tampa Bay defense could struggle against an elite Los Angeles offense.