The Jacksonville Jaguars have a key Week 12 matchup, with their road contest against the Arizona Cardinals having the potential to be the

USA Today's NFL experts make their picks for a Week 12 showdown between the Arizona Cardinals and Jacksonville Jaguars

Arizona Cardinals wide receiver Marvin Harrison Jr. has been ruled out of Sunday's game against the Jacksonville Jaguars. This will be the second consecutive game that Harrison Jr. has missed after having surgery for appendicitis.

Everything you need to know about the NFL match between Arizona Cardinals and Jacksonville Jaguars, as well as kick-off time and team news

Arizona Cardinals wide receiver Marvin Harrison Jr. will miss Sunday's game against the Jacksonville Jaguars. On Wednesday, Cardinals head coach Jonathan Gannon told reporters Harrison and running back Emari Demercado will be sidelined for the upcoming contest.

Veteran quarterback Jacoby Brissett’s 10-year NFL career has included several twists and turns. He has been a project, a starter, a backup, a Super Bowl champion and soldiered through some mediocre seasons.

The Jaguars (6-4) enter Sunday's game against the Cardinals with a chance to make some serious progress in the AFC playoff race. They will be going against a Cardinals team that clearly has its back on the wall, however, and a veteran quarterback in Jacoby Brissett who has been productive since placed in the starting lineup.

The Jacksonville Jaguars had their second practice of the week on Thursday in preparation for Sunday’s game against the Arizona Cardinals and released their second injury report of the week. The only changes from Wednesday were defensive tackle Arik Armstead and safety Andrew Wingard,