RMD Open

High-intensity interval and resistance training programme improves pain and fatigue outcomes in people with systemic sclerosis: a European multicentre randomised con…

Background Pain and fatigue are among the most debilitating symptoms of systemic sclerosis (SSc), severely impairing quality ...
RMD Open

Strengths and limitations of the EULAR definition for difficult-to-treat rheumatoid arthritis

The management of rheumatoid arthritis (RA) has significantly improved, but a substantial number of patients still experience ...
rmdopen.bmj

Optical coherence tomography angiography detects retinal microvascular changes in giant cell arteritis: the potential protective role of aortitis

Objectives To evaluate the diagnostic utility of optical coherence tomography angiography (OCTA)-derived biomarkers in patients with giant cell arteritis (GCA) and to advance the pathophysiological ...
rmdopen.bmj

Diagnostic performance and reliability of robotic ultrasonography and artificial intelligence-driven synovitis assessment in rheumatoid arthritis: results from the Controlled ...

Aim To evaluate the reliability and diagnostic performance of artificial intelligence (AI) driven robotic ultrasonography (RUS) compared with human ultrasonography (HUS) performed by a trained ...
rmdopen.bmj

Haematological malignancies in systemic sclerosis: a population-based nationwide register study

Objectives (1) To assess the risk of haematological malignancies in individuals with systemic sclerosis (SSc) compared with individuals without SSc; (2) to explore how the risk varies across groups ...
rmdopen.bmj

Invasive fungal infections in patients with rheumatoid arthritis: an explorative analysis from the German RABBIT register

Objectives To explore characteristics and treatment of patients with rheumatoid arthritis (RA) with invasive fungal infections (IFIs) and to describe infection details and outcome. Methods IFIs ...
rmdopen.bmj

Ultrasound-guided core needle biopsy of the parotid gland in Sjögren’s disease: a promising tool towards precision medicine

Background Disappointing outcomes in Sjögren’s disease (SjD) trials underscore the need for reliable, sensitive endpoints. Histological assessment holds promise, but a minimally invasive, repeatable ...
rmdopen.bmj

Sustained resolution of enthesitis and peripheral arthritis over 104 weeks with bimekizumab in axial spondyloarthritis

Background Bimekizumab (BKZ), a monoclonal IgG1 antibody that selectively inhibits interleukin (IL)-17F in addition to IL-17A, has demonstrated 2-year efficacy in non-radiographic axial ...
rmdopen.bmj

Instruments for measuring fatigue in people with rheumatic and musculoskeletal diseases: a systematic review of measurement properties

Objective To summarise the measurement properties of instruments used to assess fatigue in people with rheumatic and musculoskeletal diseases (RMDs). Methods A systematic review (SR) of measurement ...
rmdopen.bmj

Long-term safety and efficacy of upadacitinib in Japanese patients with rheumatoid arthritis and inadequate response to conventional synthetic disease-modifying antirheumatic ...

Objective To assess the long-term safety and efficacy of upadacitinib over 5 years in Japanese patients with moderate-to-severe active rheumatoid arthritis and an inadequate response to stable doses ...
rmdopen.bmj

AI-based HRCT quantification reveals DLCO and TLC as key determinants of ILD severity in connective tissue diseases

Objective Interstitial lung disease (ILD) represents the most common and severe organ manifestation observed in patients diagnosed with connective tissue diseases (CTDs). The aim of this retrospective ...